Cardiac Transgenesis With The Tetracycline Transactivator Changes Myocardial Function And Gene Expression

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Cardiac Transgenesis With The Tetracycline Transactivator Changes Myocardial Function And Gene Expression

Mccloskey Dt; Turnbull Lynne; Swigart Pm; Zambon Ac; Turcato S; Joho S; Grossman W; Conklin Br; Simpson Pc; Baker Anthony
URI: http://hdl.handle.net/10453/9715
Date: 2005

Abstract:

The cardiac-specific tetracycline-regulated gene expression system (tet-system) is a powerful tool using double-transgenic mice. The cardiac alpha-myosin heavy chain promoter (alpha MHC) drives lifetime expression of a tetracycline-inhibited transcriptio

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