Alpha(1)-Adrenergic Receptors Prevent A Maladaptive Cardiac Response To Pressure Overload

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Alpha(1)-Adrenergic Receptors Prevent A Maladaptive Cardiac Response To Pressure Overload

O'Connell T; Swigart Pm; Rodrigo Mc; Ishizaka S; Joho S; Turnbull Lynne; Tecott Lh; Baker Anthony; Foster E; Grossman W; Simpson Pc
URI: http://hdl.handle.net/10453/9639
Date: 2006

Abstract:

An alpha(1)-adrenergic receptor (alpha(1)-AR) antagonist increased heart failure in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT), but it is unknown whether this adverse result was due to alpha(1)-AR inhibition

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