Association of SLC11A1 promoter polymorphisms with the incidence of autoimmune and inflammatory diseases: A meta-analysis

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Association of SLC11A1 promoter polymorphisms with the incidence of autoimmune and inflammatory diseases: A meta-analysis

O'Brien Bronwyn; Archer Nicholas; Simpson Ann; Torpy Fraser; Nassif Najah
URI: http://hdl.handle.net/10453/9516
Date: 2008

Abstract:

Solute carrier family 11 member a1 (SLC11A1) exerts pleiotropic effects on macrophage function. Expression of SLC11A1 is regulated by a (GT)(n) microsatellite promoter repeat polymorphism of which nine alleles have been described. Enhanced activation of

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