Analysis of sedimentation equilibrium results obtained with indefinitely self-associating systems using a procedure based on Laplace transformation

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dc.contributor.author Nichol, L en_US
dc.contributor.author Jeffrey, P en_US
dc.contributor.author Milthorpe, Bruce en_US
dc.contributor.editor en_US
dc.date.accessioned 2010-05-28T09:43:23Z
dc.date.available 2010-05-28T09:43:23Z
dc.date.issued 1976 en_US
dc.identifier 2008004100 en_US
dc.identifier.citation Nichol L, Jeffrey P, and Milthorpe Bruce 1976, 'Analysis of sedimentation equilibrium results obtained with indefinitely self-associating systems using a procedure based on Laplace transformation', American Chemical Society, vol. 80, no. 10, pp. 1071-1075. en_US
dc.identifier.issn 0022-3654 en_US
dc.identifier.other C1UNSUBMIT en_US
dc.identifier.uri http://hdl.handle.net/10453/8467
dc.description.abstract Equations are developed in closed form which permit the simulation of the distribution of total concentration vs. radial distance obtainable in the sedimentation equilibrium of a system of specified initial concentration undergoing indefinite self-association. Simulated distributions obtained with a variety of systems involving one or more equilibrium constants are used to test an analysis procedure which fits the distribution to a function capable of inverse Laplace transformation and leads to a specification of the relative amounts of the species in the cell as a function of their molecular weights. It is shown that such results may be related to the equilibrium concentrations of oligomeric forms at each radial distance, thereby permitting successive equilibrium constants appropriate to the indefinite self-association to be estimated. en_US
dc.language en_US
dc.publisher American Chemical Society en_US
dc.relation.isbasedon http://dx.doi.org/10.1021/j100551a010 en_US
dc.title Analysis of sedimentation equilibrium results obtained with indefinitely self-associating systems using a procedure based on Laplace transformation en_US
dc.parent Journal of Physical Chemistry en_US
dc.journal.volume 80 en_US
dc.journal.number 10 en_US
dc.publocation Washington DC, USA en_US
dc.identifier.startpage 1071 en_US
dc.identifier.endpage 1075 en_US
dc.cauo.name SCI.Medical and Molecular Biosciences en_US
dc.conference Verified OK en_US
dc.for 030600 en_US
dc.personcode 0000049740 en_US
dc.personcode 0000049735 en_US
dc.personcode 105631 en_US
dc.percentage 100 en_US
dc.classification.name Physical Chemistry (incl. Structural en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords NA en_US
dc.staffid 105631 en_US


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