Abstract:
Current bone graft materials are mainly produced from coralline hydroxyapatite (HAp).
Due to the nature of conversion process, commercial coralline HAp has retained coral or CaC03 and
the structure possesses nanopores within the inter pore trabeculae resulting in high dissolution rates.
Under certain conditions these features reduce durability and strength respectively and are not
utilised where high structural strength is required. To overcome these limitations, a new-patented
coral double-conversion technique has been developed.
The current technique involves two-stage application route where in the first stage complete
conversion of coral to pure HAp is achieved. In the second stage a sol-gel derived HAp nanocoating
is directly applied to cover the micro and nano-pores within the intra pore material, whilst
maintaining the large pores. Biaxial strength was improved due to this unique double treatment.
This application is expected to result in enhanced durability and longevity due to monophasic
hydroxyapatite structure and strength in the physiological environment.
It is anticipated that this new material can be applied to load bearing bone graft applications where
high strength requirements are pertinent.
