Hydrazine compounds inhibit glycation of low-density lipoproteins and prevent the in vitro formation of model foam cells from glycolaldehyde-modified low-density lipoproteins

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dc.contributor.author Brown, Bronwyn en_US
dc.contributor.author Mahroof, F en_US
dc.contributor.author Cook, N en_US
dc.contributor.author Van Reyk, David en_US
dc.contributor.author Davies, Michael en_US
dc.date.accessioned 2009-12-21T02:34:22Z
dc.date.available 2009-12-21T02:34:22Z
dc.date.issued 2006 en_US
dc.identifier 2006003932 en_US
dc.identifier.citation Brown Bronwyn et al. 2006, 'Hydrazine compounds inhibit glycation of low-density lipoproteins and prevent the in vitro formation of model foam cells from glycolaldehyde-modified low-density lipoproteins', Springer, vol. 49, no. 4, pp. 775-783. en_US
dc.identifier.issn 0012-186X en_US
dc.identifier.other C1 en_US
dc.identifier.uri http://hdl.handle.net/10453/4678
dc.description.abstract Aims/hypothesis: Previous studies have shown that glycation of LDL by methylglyoxal and glycolaldehyde, in the absence of significant oxidation, results in lipid accumulation in macrophage cells. Such foam cells are a hallmark of atherosclerosis. In this en_US
dc.publisher Springer en_US
dc.relation.hasversion Accepted manuscript version en_US
dc.relation.isbasedon http://dx.doi.org/10.1007/s00125-006-0137-3 en_US
dc.rights The original publication is available at www.springerlink.com en_US
dc.title Hydrazine compounds inhibit glycation of low-density lipoproteins and prevent the in vitro formation of model foam cells from glycolaldehyde-modified low-density lipoproteins en_US
dc.parent Diabetologia en_US
dc.journal.volume 49 en_US
dc.journal.number 4 en_US
dc.publocation New York, USA en_US
dc.identifier.startpage 775 en_US
dc.identifier.endpage 783 en_US
dc.cauo.name SCI.Medical and Molecular Biosciences en_US
dc.conference Verified OK en_US
dc.for 110300 en_US
dc.personcode 0000028296 en_US
dc.personcode 0000027765 en_US
dc.personcode 0000027766 en_US
dc.personcode 000788 en_US
dc.personcode 0000045917 en_US
dc.percentage 100 en_US
dc.classification.name Clinical Sciences en_US
dc.classification.type FOR-08 en_US
dc.description.keywords aldehydes; apolipoprotein B; atherosclerosis; cholesterol esters; foam cells; glycation; hydrazines; low-density lipoproteins; macrophages; protein modification en_US


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