A Golden bullet? Selective targeting of Toxoplasma gondii Tachyzoites using antibody-functionalised gold nanorods

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dc.contributor.author Pissuwan, Dakrong en_US
dc.contributor.author Valenzuela, Stella en_US
dc.contributor.author Miller, Catherine en_US
dc.contributor.author Cortie, Michael en_US
dc.date.accessioned 2009-12-21T02:33:04Z
dc.date.available 2009-12-21T02:33:04Z
dc.date.issued 2007 en_US
dc.identifier 2007000166 en_US
dc.identifier.citation Pissuwan Dakrong et al. 2007, 'A Golden bullet? Selective targeting of Toxoplasma gondii Tachyzoites using antibody-functionalised gold nanorods', American Chemical Society, vol. 7, no. 12, pp. 3808-3812. en_US
dc.identifier.issn 1530-6984 en_US
dc.identifier.other C1 en_US
dc.identifier.uri http://hdl.handle.net/10453/4378
dc.description.abstract Conjugates of gold nanoparticles and antibodies have useful functionalities. Here we show how they can be used to selectively target and destroy parasitic protozoans. Gold nanorods were conjugated with an anti-Toxoplasma gondii antibody and used to target the extracellular tachyzoite which is an infectious from on an obligate parasite Toxoplasma gondii. Subsequent laser irradiation was used to kill the targeted protozoans. This concept provides a new paradigm for the treatment of parasitic protozoans. en_US
dc.publisher American Chemical Society en_US
dc.relation.isbasedon http://dx.doi.org/10.1021/nl072377+ en_US
dc.title A Golden bullet? Selective targeting of Toxoplasma gondii Tachyzoites using antibody-functionalised gold nanorods en_US
dc.parent Nano Letters en_US
dc.journal.volume 7 en_US
dc.journal.number 12 en_US
dc.publocation Washington DC, USA en_US
dc.identifier.startpage 3808 en_US
dc.identifier.endpage 3812 en_US
dc.cauo.name SCI.Faculty of Science en_US
dc.conference Verified OK en_US
dc.for 030600 en_US
dc.personcode 102551 en_US
dc.personcode 010690 en_US
dc.personcode 970043 en_US
dc.personcode 020302 en_US
dc.percentage 100 en_US
dc.classification.name Physical Chemistry (incl. Structural en_US
dc.classification.type FOR-08 en_US
dc.staffid 020302 en_US


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