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Browsing 06 Biological Sciences by Author

Browsing 06 Biological Sciences by Author "Walker Mark"

Now showing items 1-11 of 11

An aromatic amino acid auxotrophic mutant of Bordetella bronchiseptica is attenuated and immunogenic in a mouse model of infection

Mcarthur Jason; West Nicholas; Cole J; Jungnitz Heidrun; Guzman Carlos; Chin James; Lehrbach Phillip; Djordjevic Steven; Walker Mark (Wiley-Blackwell Publishing Ltd., 2003)

We have constructed an aromatic amino acid auxotrophic mutant of Bordetella bronchiseptica, harbouring mutations in aroA and trpE to investigate the use of such a strain as a live-attenuated vaccine. B. bronchiseptica aroA ...
Characterization of cleavage events in the multifunctional cilium adhesin Mhp684 (P146) reveals a mechanism by which Mycoplasma hyopneumoniae regulates surface topography

Bogema Daniel; Deutscher Ania; Woolley Lauren; Seymour Lisa; Raymond Benjamin; Tacchi Jessica; Padula Matthew; Dixon Nicholas; Minion F. Chris; Jenkins Cheryl; Walker Mark; Djordjevic Steven (American Society for Microbiology, 2012)

Mycoplasma hyopneumoniae causes enormous economic losses to swine production worldwide by colonizing the ciliated epithelium in the porcine respiratory tract, resulting in widespread damage to the mucociliary escalator, ...
Mhp 107 is a member of the multifunctional adhesin family of Mycoplasma hyopneumoniae

Seymour L; Falconer Linda; Deutscher A; Minion F. Chris; Padula Matthew; Dixon Nicholas; Djordjevic Steven; Walker Mark (American Society for Biochemistry and Molecular Biology Inc, 2011)

Mycoplasma hyopneumoniae is the causative pathogen of porcine enzootic pneumonia, an economically significant disease that disrupts the mucociliary escalator in the swine respiratory tract. Expression of Mhp107, a P97 ...
Mhp182 (P102) binds fibronectin and contributes to the recruitment of plasmin(ogen) to the Mycoplasma hyopneumoniae cell surface

Seymour Lisa; Jenkins Cheryl; Deutscher Ania; Raymond Benjamin; Padula Matthew; Tacchi Jessica; Bogema Daniel; Eamens Graeme; Woolley Lauren; Dixon Nicholas; Walker Mark; Djordjevic Steven (Wiley-Blackwell, 2012)

Mycoplasma hyopneumoniae is a major, economically damaging respiratory pathogen. Although M. hyopneumoniae cells bind plasminogen, the identification of plasminogen-binding surface proteins and the biological ramifications ...
Multiple antibiotic resistance gene recruitment onto the enterohemorrhagic Escherichia coli virulence plasmid

Venturini C; Beatson Scott; Djordjevic Steven; Walker Mark (Federation of American Societies for Experimental Biology, 2010)

EnterohemOiThagic Esdlerichia coli (EHEC) strains are zoonotic pathogens responsible for a range of severe human disease. The repertoire of virulence determinants promoting EHEC disease is encoded on both the main chromosome ...
Mycoplasma hyopneumoniae surface proteins Mhp385 and Mhp384 bind host cilia and glycosaminoglycans and are endoproteolytically processed by proteases that recognize different cleavage motifs

Deutscher Ania; Tacchi Jessica; Minion F. Chris; Padula Matthew; Crossett Ben; Bogema Daniel; Jenkins Cheryl; Kuit Tracey; Walker Mark; Djordjevic Steven (American Chemical Society, 2012)

P97 and P102 paralogues occur as endoproteolytic cleavage fragments on the surface of Mycoplasma hyopneumoniae that bind glycosaminoglycans, plasminogen, and fibronectin and perform essential roles in colonization of ...
P159 is a proteolytically processed, surface adhesin of Mycoplasma hyopneumoniae:defined domains of P159 bind heparin and promote adherence to eukaryote cells

Burnett Tracey; Dinkla Katrin; Rohde Manfred; Chhatwal Gursharan; Uphoff Cord; Srivastava Mukesh; Cordwell Stuart; Geary Steven; Liao Xiaofen; Minion F. Chris; Walker Mark; Djordjevic Steven (Blackwell Publishing Ltd, 2006)

Mycoplasma hyopneumoniae, the causative agent of porcine enzootic pneumonia, colonizes the respiratory cilia of affected swine causing significant economic losses to swine production worldwide. Heparin is known to inhibit ...
A Processed Multidomain Mycoplasma hyopneumoniae Adhesin Binds Fibronectin, Plasminogen, and Swine Respiratory Cilia

Seymour L; Deutscher Ania; Jenkins Cheryl; Kuit Tracey; Falconer Linda; Minion F. Chris; Crossett Ben; Padula Matthew; Dixon Nicholas; Djordjevic Steven; Walker Mark (American Society for Biochemistry and Molecular Biology Inc, 2010)

orcine enzootic pneumonia is a chronic respiratory disease that affects swine. The etiological agent of the disease, Mycoplasma hyopneumoniae, is a bacterium that adheres to cilia of the swine respiratory tract, resulting ...
The pyruvate dehydrogenase complex of Mycoplasma hyopneumoniae contains a novel lipoyl domain arrangement

Matic Jake; Wilton Judy; Towers Rebecca; Scarmann Anthony; Minion F. Chris; Walker Mark; Djordjevic Steven (Elsevier Inc, 2003)

The genes encoding the pyruvate dehydrogenase (PDH) complex (pdhA, pdhB, pdhC and pdhD) from Mycoplasma hyopneumoniae have been cloned and sequenced. The genes are arranged into two operons, designated pdhAB and pdhCD, ...
Role of group A Streptococcus HtrA in the maturation of SpeB protease

Cole J; Aquilina J; Hains P; Henningham A; Sriprakash K; Caparon M; Nizet V; Kotb M; Cordwell Stuart; Djordjevic Steven; Walker Mark (Wiley - V C H Verlag GmbH & Co. KGaA, 2007)

The serine protease HtrA (DegP) of the human pathogen Streptococcus pyogenes (group A Streptococcus; GAS) is localized to the ExPortal secretory microdomain and is reportedly essential for the maturation of cysteine protease ...
Sequence TTKF | QE defines the site of proteolytic cleavage in Mhp683, a novel glycosaminoglycan and cilium adhesin of Mycoplasma hyopneumoniae

Bogema Daniel; Scott Nichollas; Padula Matthew; Tacchi Jessica; Raymond Ben; Jenkins Cheryl; Cordwell Stuart; Minion F. Chris; Walker Mark; Djordjevic Steven (ASBMB, 2011)

Mycoplasma hyopneumoniae colonizes the ciliated respiratory epithelium of swine, disrupting mucociliary function and inducing chronic inflammation. P97 and P102 family members are major surface proteins of M. hyopneumoniae ...

Now showing items 1-11 of 11

Browsing 06 Biological Sciences by Author "Walker Mark"

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Browsing 06 Biological Sciences by Author "Walker Mark"