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Construction Of A Genetically Defined Salmonella-Typhi Ty2 Aroa, Aroc Mutant For The Engineering Of A Candidate Oral Typhoid Tetanus Vaccine

Chatfield Sn; Fairweather N; Charles Ian; Pickard D; Levine M A; Hone D; Posada M; Strugnell Ra; Dougan G (Butterworth-Heinemann Ltd, 1992)

The construction of a Salmonella typhi Ty2 strain harbouring defined deletions in both the aroA and aroC genes is described. These deletions have been fully defined at the molecular level by DNA sequencing and have been ...
Expression Of P.69/Pertactin From Bordetella-Pertussis In A Baculovirus/Insect Cell Expression System - Protective Properties Of The Recomnbinant Protein

Charles Ian; Rodgers B; Musgrave S; Peakman Tc; Chubb A; Fairweather N; Dougan G; Roberts Ms (Editions Scientifiques Elsevier, 1993)

The surface antigen P.69/pertactin of Bordetella pertussis has been expressed using the polyhedron promoter of baculovirus in cultured insect cells. Either full-length or truncated pm DNA was used to express P.69 pertactin. ...
Pertactin, An Arg-Gly-Asp-Containing Bordetella-Pertussis Surface Protein That Promotes Adherence Of Mammalian-Cells

Leininger E; Roberts Ms; Kenimer Jg; Charles Ian; Fairweather N; Novotny P; Brennan Mary (Natl Acad Sciences, 1991)

A 69-kDa protein has been identified on the surface of the Gram-negative pathrogen Bordetella pertussis that can elicit a protective immune response in animal models. This protein is associated with virulent strains of ...

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