Browsing 03 Chemical Sciences by Author "Sastraruji Thanapat"

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Browsing 03 Chemical Sciences by Author "Sastraruji Thanapat"

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  • Alkaloids from the Roots of Stemona aphylla 
    Mungkornasawakul Pitchaya; Chaiyong Sukanda; Sastraruji Thanapat; Jatisatienr Araya; Jatisatienr Chaiwat; Pyne Stephen; Ung Alison; Korth John; Lie Wilford (American Chemical Society, 2009)
    Three known compounds, stemofoline (1), (2?S)-hydroxystemofoline (2), and (11Z)-1?,2?-didehydrostemofoline (3), along with two new alkaloids, stemaphylline (4) and stemaphylline-N-oxide (5), have been isolated from a root ...
  • Oxidation of acyclic alkenes and allyl and benzyl ethers with DIB/t-BuOOH/Mg(OAc)2 
    Sastraruji Thanapat; Pyne S.; Ung Alison (Pergamon, 2012)
    Oxidation of (11Z)-1',2'-didehydrostemofoline with DIB/TBHP/Mg(OAc)(2)center dot 4H(2)O resulted in oxidative cleavage of the C-11-C-12 double bond instead of the desired allylic oxidation of the 1-butenyl side chain. ...
  • Phytochemical Investigations of Stemona curtisii and Synthetic Studies on Stemocurtisine 
    Chaiyong Sukanda; Jatisatienr Araya; Mungkornasawakul Pitchaya; Sastraruji Thanapat; Pyne S.; Ung Alison; Urathamakul Thitima; Lie Wilford (American Chemical Society, 2010)
    The isolation of two new Stemona alkaloids, 1-hydroxyprotostemonine and stemocurtisine N-oxide, and a new benzofuran, stemofuran L, from the root extracts of Stemona curtisii is reported. The major known alkaloids from ...
  • Phytochemical Studies on Stemona Plants: Isolation of New Tuberostemonine and Stemofoline Alkaloids 
    Sastraruji Thanapat; Jatisatienr Araya; Issakul Kritchaya; Pyne Stephen; Ung Alison; Lie Wilford; Williams Morwenna (Natural Product Inc., 2006)
    Six new stemofoline alkaloids, (2`R)-hydroxystemofoline (5), (3`R)-stemofolenol (6), (3`S)-stemofolenol (7), 1`,2`-didehydrostemofoline-N-oxide (8), the first C19 stemofoline alkaloid, methylstemofoline (9), and the first ...
  • Semisynthesis and Biological Activity of Stemofoline Alkaloids 
    Baird Morwenna; Pyne Stephen; Ung Alison; Lie Wilford; Sastraruji Thanapat; Jatisatienr Araya; Jatisatienr Chaiwat; Dheeranupattana Srisulak; Lowlam Jaturong; Boonchalermkit Sukanya (American Chemical Society, 2009)
    The semisynthesis of the Stemona alkaloids (3?R)-stemofolenol (1), (3?S)-stemofolenol (2), methylstemofoline (3), and (3?S)-hydroxystemofoline (5) and the unnatural analogues (11E)-methylstemofoline (15) and 3?R-hydroxystemofoline ...
  • Synthesis of alkaloid-like compounds via the bridging Ritter Reaction 
    Hemtasin Chulida; Ung Alison; Kanokmedhakul Somdej; Kanokmedhakul Kwanjai; Bishop Roger; Sastraruji Thanapat; Bishop David (Springer, 2012)
    Alkaloid-like compounds containing a benzo[c]azepine core structure were successfully prepared in three steps from H-dibenzo[a,d]cyclohepten-5-ol via the bridging Ritter reaction. Biological studies of these compounds ...
  • Synthesis of stemofoline analogues as acetylcholinesterase inhibitors 
    Sastraruji Kwankamol; Sastraruji Thanapat; Ung Alison; Griffith Renate; Jatisatienr Araya; Pyne Stephen (Elsevier Inc, 2012)
    Thirty-two new stemofoline analogues were prepared from didehydrostemofoline for studies as AChE inhibitors. C-3 Side-chain modified amino, carbamate, triazole and oxazole stemofoline derivatives were prepared. In general ...