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Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome

Gracanin Michelle; Lam Magdalena; Morgan Philip; Rodgers Kenneth; Hawkins Clare; Davies Michael (Pergamon, 2011)

Proteins are major biological targets for oxidative damage within cells because of their high abundance and rapid rates of reaction with radicals and singlet oxygen. These reactions generate high yields of hydroperoxides. ...
Glycation of low-density lipoprotein results in the time- dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages

Brown Bronwyn; Rashid Imran; Van Reyk David; Davies Michael (Blackwell Science, 2002)
Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides

Headlam Ha; Gracanin M; Rodgers Kenneth; Davies Michael (Elsevier Science Inc, 2006)

Reaction of radicals ill the presence Of O-2, and singlet oxygen, with some amino acids, peptides, and proteins yields hydroperoxides. These species are key intermediates in chain reactions and protein damage. Previously ...

Now showing items 1-3 of 3