ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures

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dc.contributor.author Herzig, Volker en_US
dc.contributor.author Wood, David en_US
dc.contributor.author Newell, Felicity en_US
dc.contributor.author Chaumeil, Pierre-Alain en_US
dc.contributor.author Kaas, Quentin en_US
dc.contributor.author Binford, Greta en_US
dc.contributor.author Nicholson, Graham en_US
dc.contributor.author Gorse, Dominique en_US
dc.contributor.author King, Glenn en_US
dc.contributor.editor en_US
dc.date.accessioned 2012-10-12T03:37:56Z
dc.date.available 2012-10-12T03:37:56Z
dc.date.issued 2011 en_US
dc.identifier 2009008706 en_US
dc.identifier.citation Herzig Volker et al. 2011, 'ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures', Nucleic Acids Research, Oxford Univ Press United Kingdom, Oxford en_US
dc.identifier.issn 0305-1048 en_US
dc.identifier.other C5 en_US
dc.identifier.uri http://hdl.handle.net/10453/19437
dc.description.abstract ArachnoServer (www.arachnoserver.org) is a manually curated database providing information on the sequence, structure and biological activity of protein toxins from spider venoms. These proteins are of interest to a wide range of biologists due to their diverse applications in medicine, neuroscience, pharmacology, drug discovery and agriculture. ArachnoServer currently manages 1078 protein sequences, 759 nucleic acid sequences and 56 protein structures. Key features of ArachnoServer include a molecular target ontology designed specifically for venom toxins, current and historic taxonomic information and a powerful advanced search interface. The following significant improvements have been implemented in version 2.0: (i) the average and monoisotopic molecular masses of both the reduced and oxidized form of each mature toxin are provided; (ii) the advanced search feature now enables searches on the basis of toxin mass, external database accession numbers and publication date in ArachnoServer; (iii) toxins can now be browsed on the basis of their phyletic specificity; (iv) rapid BLAST searches based on the mature toxin sequence can be performed directly from the toxin card; (v) private silos can be requested from research groups engaged in venoms-based research, enabling them to easily manage and securely store data during the process of toxin discovery; and (vi) a detailed user manual is now available. en_US
dc.language en_US
dc.publisher Oxford Univ Press United Kingdom en_US
dc.relation.isbasedon http://dx.doi.org/10.1093/nar/gkq1058 en_US
dc.title ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures en_US
dc.parent Nucleic Acids Research en_US
dc.journal.volume 39 en_US
dc.journal.number suppl 1 en_US
dc.publocation Oxford en_US
dc.identifier.startpage D653 en_US
dc.identifier.endpage D657 en_US
dc.cauo.name SCI.Medical and Molecular Biosciences en_US
dc.conference Verified OK en_US
dc.for 111506 en_US
dc.personcode 0000064780 en_US
dc.personcode 0000064781 en_US
dc.personcode 0000064782 en_US
dc.personcode 0000064783 en_US
dc.personcode 0000064784 en_US
dc.personcode 0000064785 en_US
dc.personcode 870145 en_US
dc.personcode 0000064786 en_US
dc.personcode 0000043010 en_US
dc.percentage 100 en_US
dc.classification.name Toxicology (incl. Clinical Toxicology) en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords PROT PROTEIN KNOWLEDGEBASE; VENOMS; NOMENCLATURE; COMPLEXITY; DATABASE en_US


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