Surgical Adhesion and Its Prevention

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dc.contributor.author Godara, Pankaj en_US
dc.contributor.author Milthorpe, Bruce en_US
dc.contributor.editor P. Ducheyne, K.E. Healy, D.W. Hutmacher, D.W. Grainger, C.J. Kirkpatrick en_US
dc.date.accessioned 2012-10-12T03:37:48Z
dc.date.available 2012-10-12T03:37:48Z
dc.date.issued 2011 en_US
dc.identifier 2010006807 en_US
dc.identifier.citation Godara Pankaj and Milthorpe Bruce 2011, 'Surgical Adhesion and Its Prevention', Comprehensive Biomaterials, Elsevier, USA en_US
dc.identifier.issn 978-0-08-055302-3 en_US
dc.identifier.other B3 en_US
dc.identifier.uri http://hdl.handle.net/10453/19434
dc.description.abstract Adhesion of freely moving tissues and organs due to surgical injury and trauma can be a serious postoperative complication. High rates of incidence due to surgical intervention, especially associated with abdominal procedures, have been reported. This chapter gives an introduction to the formation of adhesions, with particular focus on peritoneum, urinary and reproductive (female) systems, tendon, ligament, joint, and pericardium. A number of techniques, treatments, and materials have been proposed for the prevention/reduction of adhesion formation. Of these, barrier methods are considered the only effective method currently available. An overview of biomaterials currently used as barriers for postsurgical tissue adhesion is presented. Current clinical practice utilizes solid membranes/mechanical barriers, spray-on, and gel and liquid barriers. These barriers can be either resorbable, nonresorbable, or a combination of both. Complications of barrier films are examined, and design criteria for barrier membranes are presented. Adhesion formation can be beneficial in particular circumstances, such as for anchoring implants, and these uses are commented upon. Much advancement has been made in this area, thanks to the increasing knowledge and understanding regarding the events that control adhesion formation, but there is still a long way to go before an optimum solution to this problem is found. en_US
dc.language Yes en_US
dc.publisher Elsevier en_US
dc.relation.isbasedon http://dx.doi.org/10.1016/B978-0-08-055294-1.00244-0 en_US
dc.title Surgical Adhesion and Its Prevention en_US
dc.parent Comprehensive Biomaterials en_US
dc.journal.volume en_US
dc.journal.number en_US
dc.publocation USA en_US
dc.identifier.startpage 561 en_US
dc.identifier.endpage 572 en_US
dc.cauo.name SCI.Medical and Molecular Biosciences en_US
dc.conference Verified OK en_US
dc.for 090300 en_US
dc.personcode 108424 en_US
dc.personcode 105631 en_US
dc.percentage 100 en_US
dc.classification.name Biomedical Engineering en_US
dc.classification.type FOR-08 en_US
dc.edition 1 en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords Abdominal surgery; Adhesion barrier; Adhesion formation; Biocompatibility; Biomaterial; Cardiac surgery; Fibrolysis; Fibrosis; Hyaluronic acid; Resorbable polymers; Sodium carboxymethylcellulose; Tendon surgery; Tissue adhesion en_US
dc.staffid en_US
dc.staffid 105631 en_US


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