Quality of life and survival in the 2 years after surgery for non-small-cell lung cancer

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dc.contributor.author Kenny, Patricia en_US
dc.contributor.author King, Madeleine en_US
dc.contributor.author Viney, Rosalie en_US
dc.contributor.author Boyer, Michael en_US
dc.contributor.author Pollicino, Christine en_US
dc.contributor.author Mclean, Jocelyn en_US
dc.contributor.author Fulham, Michael en_US
dc.contributor.author Mccaughan, Brian en_US
dc.contributor.editor en_US
dc.date.accessioned 2012-02-10T06:09:40Z
dc.date.available 2012-02-10T06:09:40Z
dc.date.issued 2008 en_US
dc.identifier 2011000540 en_US
dc.identifier.citation Kenny Patsy et al. 2008, 'Quality of life and survival in the 2 years after surgery for non-small-cell lung cancer', Amer Soc Clinical Oncology, vol. 26, no. 2, pp. 233-241. en_US
dc.identifier.issn 0732-183X en_US
dc.identifier.other C5 en_US
dc.identifier.uri http://hdl.handle.net/10453/17091
dc.description.abstract Purpose Although surgery for early-stage non-small-cell lung cancer ( NSCLC) is known to have a substantial impact on health-related quality of life (HRQOL), there are few published studies about HRQOL in the longer term. This article examines HRQOL and survival in the 2 years after surgery. Patients and Methods Patients with clinical stage I or II NSCLC (n = 173) completed HRQOL questionnaires before surgery, at discharge, 1 month after surgery, and then every 4 months for 2 years. HRQOL was measured with a generic cancer questionnaire (European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire [ EORTC-QLQ] C30) and a lung cancer-specific questionnaire (EORTC QLQ-LC13). Data were analyzed to examine the impact of surgery and any subsequent therapy, and to describe the trajectories of those who remained disease free at 2 years and those with recurrent cancer diagnosed during follow-up. Results Disease recurred within 2 years for 36% of patients and 2-year survival was 65%. Surgery substantially reduced HRQOL across all dimensions except emotional functioning. HRQOL improved in the 2 years after surgery for patients without disease recurrence, although approximately half continued to experience symptoms and functional limitations. For those with recurrence within 2 years, there was some early postoperative recovery in HRQOL, with subsequent deterioration across most dimensions. en_US
dc.language en_US
dc.publisher Amer Soc Clinical Oncology en_US
dc.relation.isbasedon http://dx.doi.org/10.1200/JCO.2006.07.7230 en_US
dc.title Quality of life and survival in the 2 years after surgery for non-small-cell lung cancer en_US
dc.parent Journal of Clinical Oncology en_US
dc.journal.volume 26 en_US
dc.journal.number 2 en_US
dc.publocation USA en_US
dc.identifier.startpage 233 en_US
dc.identifier.endpage 241 en_US
dc.cauo.name BUS.Faculty of Business en_US
dc.conference Verified OK en_US
dc.for 111200 en_US
dc.personcode 106668 en_US
dc.personcode 020118 en_US
dc.personcode 020117 en_US
dc.personcode 0000022092 en_US
dc.personcode 0000017998 en_US
dc.personcode 0000022093 en_US
dc.personcode 0000022095 en_US
dc.personcode 0000022094 en_US
dc.percentage 100 en_US
dc.classification.name Oncology and Carcinogenesis en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords NA en_US

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