The ambiguous life of Dientamoeba fragilis: the need to investigate current hypotheses on transmission?

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dc.contributor.author Barratt, Joel en_US
dc.contributor.author Harkness, Jock en_US
dc.contributor.author Marriott, Debbie en_US
dc.contributor.author Ellis, John en_US
dc.contributor.author Stark, Damien en_US
dc.contributor.editor en_US
dc.date.accessioned 2012-02-10T06:09:10Z
dc.date.available 2012-02-10T06:09:10Z
dc.date.issued 2011 en_US
dc.identifier 2010000134 en_US
dc.identifier.citation Barratt Joel et al. 2011, 'The ambiguous life of Dientamoeba fragilis: the need to investigate current hypotheses on transmission?', Cambridge University Press, vol. 138, no. 5, pp. 557-572. en_US
dc.identifier.issn 0031-1820 en_US
dc.identifier.other C1 en_US
dc.identifier.uri http://hdl.handle.net/10453/16938
dc.description.abstract Dientamoeba fragilis is an inhabitant of the human bowel and is associated with gastrointestinal illness. Despite its discovery over a century ago, the details of Dientamoeba?s life cycle are unclear and its mode of transmission is unknown. Several theories exist which attempt to explain how Dientamoeba may be transmitted. One theory suggests that animals are responsible for the transmission of Dientamoeba. However, reports of Dientamoeba in animals are sporadic and most are not supported by molecular evidence. Another theory suggests that Dientamoeba may be transmitted via the ova of a helminth. Given that the closest relative of Dientamoeba is transmitted via the ova of a helminth, this theory seems plausible. It has also been suggested that Dientamoeba could be transmitted directly between humans. This theory also seems plausible given that other relatives of Dientamoeba are transmitted in this way. Despite numerous investigations, Dientamoeba?s mode of transmission remains unknown. This review discusses the strengths and weaknesses of theories relating to Dientamoeba?s mode of transmission and, by doing so, indicates where gaps in current knowledge exist. Where information is lacking, suggestions are made as to how future research could improve our knowledge on the life cycle of Dientamoeba. en_US
dc.language en_US
dc.publisher Cambridge University Press en_US
dc.relation.isbasedon http://dx.doi.org/10.1017/S0031182010001733 en_US
dc.title The ambiguous life of Dientamoeba fragilis: the need to investigate current hypotheses on transmission? en_US
dc.parent Parasitology en_US
dc.journal.volume 138 en_US
dc.journal.number 5 en_US
dc.publocation Cambridge, UK en_US
dc.identifier.startpage 557 en_US
dc.identifier.endpage 572 en_US
dc.cauo.name SCI.Faculty of Science en_US
dc.conference Verified OK en_US
dc.for 110803 en_US
dc.personcode 101335 en_US
dc.personcode 100210 en_US
dc.personcode 100209 en_US
dc.personcode 910945 en_US
dc.personcode 104964 en_US
dc.percentage 100 en_US
dc.classification.name Medical Parasitology en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords Dientamoeba fragilis is an inhabitant of the human bowel and is associated with gastrointestinal illness. Despite its discovery over a century ago, the details of Dientamoeba?s life cycle are unclear and its mode of transmission is unknown. Several theories exist which attempt to explain how Dientamoeba may be transmitted. One theory suggests that animals are responsible for the transmission of Dientamoeba. However, reports of Dientamoeba in animals are sporadic and most are not supported by molecular evidence. Another theory suggests that Dientamoeba may be transmitted via the ova of a helminth. Given that the closest relative of Dientamoeba is transmitted via the ova of a helminth, this theory seems plausible. It has also been suggested that Dientamoeba could be transmitted directly between humans. This theory also seems plausible given that other relatives of Dientamoeba are transmitted in this way. Despite numerous investigations, Dientamoeba?s mode of transmission remains unknown. This review discusses the strengths and weaknesses of theories relating to Dientamoeba?s mode of transmission and, by doing so, indicates where gaps in current knowledge exist. Where information is lacking, suggestions are made as to how future research could improve our knowledge on the life cycle of Dientamoeba. en_US
dc.staffid 104964 en_US


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