Destabilizing role of cathepsin S in murine atherosclerotic plaques

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Destabilizing role of cathepsin S in murine atherosclerotic plaques

Rodgers Kenneth; Watkins Dj; Miller Al; Chan Py; Karanam S; Brissette Wh; Long Cj; Jackson Cl
URI: http://hdl.handle.net/10453/16872
Date: 2006

Abstract:

Objective - Lysosomal proteinases have been implicated in a number of pathologies associated with extracellular matrix breakdown. Therefore, we investigated the possibility that the lysosomal proteinase cathepsin S may be involved in atherosclerotic plaq

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