Amnesic shellfish poisoning toxins in bivalve molluscs in Ireland

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Show simple item record James, Kevin en_US Gillman, Marion en_US Amandi, Monica en_US Lopez-Rievra, Americo en_US Puente, Patricia en_US Lehane, Mary en_US Mitrovic, Simon en_US Furey, Ambrose en_US
dc.contributor.editor en_US 2012-02-02T11:01:16Z 2012-02-02T11:01:16Z 2005 en_US
dc.identifier 2010001796 en_US
dc.identifier.citation James Kevin et al. 2005, 'Amnesic shellfish poisoning toxins in bivalve molluscs in Ireland', Elsevier Science, vol. 46, no. 8, pp. 852-858. en_US
dc.identifier.issn 0041-0101 en_US
dc.identifier.other C1UNSUBMIT en_US
dc.description.abstract In December 1999, domoic acid (DA) a potent neurotoxin, responsible for the syndrome Amnesic Shellfish Poisoning (ASP) was detected for the first time in shellfish harvested in Ireland. Two liquid chromatography (LC) methods were applied to quantify DA in shellfish after sample clean-up using solid-phase extraction (SPE) with strong anion exchange (SAX) cartridges. Toxin detection was achieved using photodiode array ultraviolet (LC-UV) and multiple tandem mass spectrometry (LC-MSn). DA was identified in four species of bivalve shellfish collected along the west and south coastal regions of the Republic of Ireland. The amount of DA that was present in three species was within EU guideline limits for sale of shellfish (20 ?g DA/g); mussels (Mytilus edulis), <1.0 ?g DA/g; oysters (Crassostrea edulis), <5.0 ?g DA/g and razor clams (Ensis siliqua), <0.3 ?g DA/g. However, king scallops (Pecten maximus) posed a significant human health hazard with levels up to 240 ?g DA/g total tissues. Most scallop samples (55%) contained DA at levels greater than the regulatory limit. The DA levels in the digestive glands of some samples of scallops were among the highest that have ever been recorded (2820 ?g DA/g). en_US
dc.language en_US
dc.publisher Elsevier Science en_US
dc.relation.isbasedon en_US
dc.title Amnesic shellfish poisoning toxins in bivalve molluscs in Ireland en_US
dc.parent Toxicon en_US
dc.journal.volume 46 en_US
dc.journal.number 8 en_US
dc.publocation Oxford, UK en_US
dc.identifier.startpage 852 en_US
dc.identifier.endpage 858 en_US SCI.Faculty of Science en_US
dc.conference Verified OK en_US
dc.for 060800 en_US
dc.personcode 0000068832 en_US
dc.personcode 0000068835 en_US
dc.personcode 0000068836 en_US
dc.personcode 0000068837 en_US
dc.personcode 0000068838 en_US
dc.personcode 0000068839 en_US
dc.personcode 944240 en_US
dc.personcode 0000068831 en_US
dc.percentage 100 en_US Zoology en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US en_US
dc.location.activity en_US
dc.description.keywords ASP; Domoic acid; Shellfish toxin; Food safety; LC-MS en_US

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