The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans

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The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans

Jannot Guillaume; Bajan Sarah; Giguère N; Bouasker Samir; Banville Isabelle; Piquet Sandra; Hutvagner Gyorgy; Simard Martin
URI: http://hdl.handle.net/10453/14967
Date: 2011

Abstract:

Despite the importance of microRNAs (miRNAs) in gene regulation, it is unclear how the miRNA-Argonaute complex-or miRNA-induced silencing complex (miRISC)-can regulate the translation of their targets in such diverse ways. We demonstrate here a direct in

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