Design of 1,2-dioxines with anti-Candida activity: aromatic substituted 1,2-dioxines

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dc.contributor.author Macreadie, Ian en_US
dc.contributor.author Avery, Thomas en_US
dc.contributor.author Robinson, Tony en_US
dc.contributor.author Macreadie, Peter en_US
dc.contributor.author Barraclough, Miles en_US
dc.contributor.author Taylor, Dennis en_US
dc.contributor.author Tiekink, Edward en_US
dc.contributor.editor en_US
dc.date.accessioned 2012-02-02T05:39:39Z
dc.date.available 2012-02-02T05:39:39Z
dc.date.issued 2008 en_US
dc.identifier 2010001950 en_US
dc.identifier.citation Macreadie Ian et al. 2008, 'Design of 1,2-dioxines with anti-Candida activity: aromatic substituted 1,2-dioxines', Pergamon, vol. 64, no. 7, pp. 1225-1232. en_US
dc.identifier.issn 0040-4020 en_US
dc.identifier.other C1UNSUBMIT en_US
dc.identifier.uri http://hdl.handle.net/10453/14670
dc.description.abstract In an ongoing effort to rationally design new antimicrobials, 47 new 1,2-dioxines have been synthesised. Broad antifungal structure?activity relationships governing aromatically substituted epoxy-1,2-dioxines 2 and 3 and their parent 1,2-dioxines 1 were assessed primarily against the pathogenic yeast, Candida albicans, with haemolytic activity of selected examples also reported. en_US
dc.language en_US
dc.publisher Pergamon en_US
dc.relation.isbasedon http://dx.doi.org/10.1016/j.tet.2007.11.071 en_US
dc.title Design of 1,2-dioxines with anti-Candida activity: aromatic substituted 1,2-dioxines en_US
dc.parent Tetrahedron en_US
dc.journal.volume 64 en_US
dc.journal.number 7 en_US
dc.publocation United Kingdom en_US
dc.identifier.startpage 1225 en_US
dc.identifier.endpage 1232 en_US
dc.cauo.name SCI.Environmental Sciences en_US
dc.conference Verified OK en_US
dc.for 030400 en_US
dc.personcode 0000066758 en_US
dc.personcode 0000066761 en_US
dc.personcode 0000066762 en_US
dc.personcode 108249 en_US
dc.personcode 0000066763 en_US
dc.personcode 0000066764 en_US
dc.personcode 0000066765 en_US
dc.percentage 100 en_US
dc.classification.name Medicinal and Biomolecular Chemistry en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords Antifungal; 1,2-Dioxine; Candida; Epoxy-1,2-dioxine; Haemolytic activity en_US
dc.staffid en_US


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