ICP-MS-Based strategies for protein quantification

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dc.contributor.author Wang, Meng en_US
dc.contributor.author Feng, Wei-Yue en_US
dc.contributor.author Zhao, Yu-Liang en_US
dc.contributor.author Chai, Zhi-Fang en_US
dc.contributor.editor en_US
dc.date.accessioned 2012-02-02T05:26:25Z
dc.date.available 2012-02-02T05:26:25Z
dc.date.issued 2010 en_US
dc.identifier 2010003225 en_US
dc.identifier.citation Wang Meng et al. 2010, 'ICP-MS-Based strategies for protein quantification', John Wiley & Sons, Inc., vol. 29, no. 2, pp. 326-348. en_US
dc.identifier.issn 1098-2787 en_US
dc.identifier.other C1UNSUBMIT en_US
dc.identifier.uri http://hdl.handle.net/10453/14644
dc.description.abstract In the post-genomics era, proteomics has become a central branch in life sciences. An understanding of biological functions will not only rely on protein identification, but also on protein quantification in a living organism. Most of the existing methods for quantitative proteomics are based on isotope labeling combined with molecular mass spectrometry. Recently, a remarkable progress that utilizes inductively coupled plasmamass spectrometry (ICP-MS) as an attractive complement to electrospray MS and MALDI MS for protein quantification, especially for absolute quantification, has been achieved. This review will selectively discuss the recent advances of ICP-MSbased technique, which will be expected to further mature and to become one of the key methods in quantitative proteomics. en_US
dc.language en_US
dc.publisher John Wiley & Sons, Inc. en_US
dc.relation.isbasedon http://dx.doi.org/10.1039/c3an00468f en_US
dc.title ICP-MS-Based strategies for protein quantification en_US
dc.parent Mass Spectrometry Reviews en_US
dc.journal.volume 29 en_US
dc.journal.number 2 en_US
dc.publocation USA en_US
dc.identifier.startpage 326 en_US
dc.identifier.endpage 348 en_US
dc.cauo.name SCI.Faculty of Science en_US
dc.conference Verified OK en_US
dc.for 030600 en_US
dc.personcode 112014 en_US
dc.personcode 0000068160 en_US
dc.personcode 0000068185 en_US
dc.personcode 0000068186 en_US
dc.percentage 100 en_US
dc.classification.name Physical Chemistry (incl. Structural en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords elemental mass spectrometry; molecular mass spectrometry; quantitative proteomics; elemental labeling; laser ablation; isotope dilution en_US

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