Combined use of the chemitrode with osmotic minipumps for experimental brain research

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dc.contributor.author Girgis, M en_US
dc.contributor.author Kent, Jennifer en_US
dc.contributor.author Kohlhardt, S en_US
dc.contributor.author Rasko, J en_US
dc.contributor.author Stobo, P en_US
dc.contributor.editor en_US
dc.date.accessioned 2011-02-07T06:24:36Z
dc.date.available 2011-02-07T06:24:36Z
dc.date.issued 1981 en_US
dc.identifier 2007005068 en_US
dc.identifier.citation Girgis M et al. 1981, 'Combined use of the chemitrode with osmotic minipumps for experimental brain research', Elsevier, vol. 7, no. 6, pp. 719-721. en_US
dc.identifier.issn 0361-9230 en_US
dc.identifier.other C1UNSUBMIT en_US
dc.identifier.uri http://hdl.handle.net/10453/13772
dc.description.abstract This paper describes a simple-to-build minipump-chemitrode assembly which can be used for long term electrophysiological, chemical and behavioural studies. This system consists of an osmotic minipump, a cannula and an array of nine electrodes which are connected to a miniature Winchester Socket. A detailed plan for construction of both the chemitrode and the minipump-chemitrode is given together with some suggestions for possible usages in brain research(such as kindling). The osmotic minipump consists of a collapsible reservoir of flexible, impermeable material, surrounded by a sealed layer containing an osmotic agent--all of which is contained by a semipermeable membrane. Imbibed water generates hydrostatic pressure on the flexible lining of the reservoir, gradually compressing it, producing a constant flow of its contents through the delivery portal. en_US
dc.language en_US
dc.publisher Elsevier en_US
dc.relation.isbasedon http://dx.doi.org/10.1016/0361-9230(81)90125-8 en_US
dc.title Combined use of the chemitrode with osmotic minipumps for experimental brain research en_US
dc.parent Brain Research Bulletin en_US
dc.journal.volume 7 en_US
dc.journal.number 6 en_US
dc.publocation The Netherlands en_US
dc.identifier.startpage 719 en_US
dc.identifier.endpage 721 en_US
dc.cauo.name DVCRch.Institute for Sustainable Futures en_US
dc.conference Verified OK en_US
dc.for 110900 en_US
dc.personcode 0000046542 en_US
dc.personcode 104179 en_US
dc.personcode 0000046543 en_US
dc.personcode 0000046544 en_US
dc.personcode 0000046545 en_US
dc.percentage 100 en_US
dc.classification.name Neurosciences en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords Minipump-chemitrode; Behaviour; Kindling; Prostigmine; Reserpine en_US
dc.staffid en_US


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