Recombinant Bordetella-Pertussis Pertactin (P69) From The Yeast Pichia-Pastoris - High-Level Production And Immunological Properties

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Recombinant Bordetella-Pertussis Pertactin (P69) From The Yeast Pichia-Pastoris - High-Level Production And Immunological Properties

Romanos Ma; Clare Jj; Beesley Km; Rayment Fb; Ballantine Sp; Makoff Aj; Dougan G; Fairweather Nf; Charles Ian
URI: http://hdl.handle.net/10453/13749
Date: 1991

Abstract:

Acellular whooping cough vaccines are based on pertussis toxoid but their effectiveness may be increased by the addition of other Bordetella pertussis antigens. We expressed the immunogenic outer membrane protein pertactin (P69) from B. pertussis to hig

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