Characterization Of A Salmonella-Typhimurium-Aro Vaccine Strain Expressing The P.69 Antigen Of Bordetella-Pertussis

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Characterization Of A Salmonella-Typhimurium-Aro Vaccine Strain Expressing The P.69 Antigen Of Bordetella-Pertussis

Strugnell R; Dougan G; Chatfield S; Charles Ian; Fairweather N; Tite J; Li Jianchun; Beesley J; Roberts Ms
URI: http://hdl.handle.net/10453/13716
Date: 1992

Abstract:

The P.69 Bordetella pertussis protective antigen was expressed by use of the trc promoter from the chromosome of a Salmonella typhimurium aro vaccine strain, BRD509, by integrating the prn gene, encoding the 93-kDa precursor of this protein, into the aro

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