The first report of ovine cerebral neosporosis and evaluation of Neospora caninum prevalence in sheep in New South Wales

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Show simple item record Bishop, Stephanie en_US King, Jess en_US Windsor, Peter en_US Reichel, Michael en_US Ellis, John en_US Slapeta, Jan en_US
dc.contributor.editor en_US 2011-02-07T06:21:49Z 2011-02-07T06:21:49Z 2010 en_US
dc.identifier 2009003859 en_US
dc.identifier.citation Bishop Stephanie et al. 2010, 'The first report of ovine cerebral neosporosis and evaluation of Neospora caninum prevalence in sheep in New South Wales', Elsevier Inc, vol. 170, no. 1-2, pp. 137-142. en_US
dc.identifier.issn 0304-4017 en_US
dc.identifier.other C1 en_US
dc.description.abstract Presence of Neospora caninum DNA was detected in the brain and spinal cord of an adult Merino sheep suspected of dying with acute non-suppurative meningoencephalitis and mild to moderate non-suppurative myelitis. The most severe neurological lesions were found in the midbrain at the rostral coliculi with moderate to severe multifocal vasculitis and gliosis. As this was the first known occurrence of cerebral disease in sheep in Australia caused by N. caninum, we surveyed sera from five sheep properties in New South Wales (NSW) to obtain information on the likely prevalence of N. caninum infection in NSW sheep flocks. Serology using a commercial indirect enzyme-linked immunosorbent assay (ELISA) revealed no N. caninum antibody-positive sheep (n = 184). However an observed prevalence for N. caninum antibodies using a commercially available competitive ELISA was 2.2% (5/232). We conclude that although the diagnosis of fatal ovine cerebral neosporosis is of importance to our surveillance program for transmissible spongiform encephalopathy (TSE) exclusion, sheep in NSW are not commonly infected with N. caninum and this species likely plays only a minor role in the life cycle of this parasite in Australia. en_US
dc.language en_US
dc.publisher Elsevier Inc en_US
dc.relation.hasversion Accepted manuscript version en_US
dc.relation.isbasedon en_US
dc.rights NOTICE: this is the author’s version of a work that was accepted for publication in Veterinary Parasitology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Veterinary Parasitology, [Volume 170, Issues 1–2, 28 May 2010, Pages 137–142)] DOI# en_US
dc.title The first report of ovine cerebral neosporosis and evaluation of Neospora caninum prevalence in sheep in New South Wales en_US
dc.title.alternative Investigating the prevalence of Neospora caninum infection in sheep in New South Wales following suspected ovine cerebral neosporosis en_US
dc.parent Veterinary Parasitology en_US
dc.journal.volume 170 en_US
dc.journal.number 1-2 en_US
dc.publocation Amsterdam, Netherlands en_US
dc.identifier.startpage 137 en_US
dc.identifier.endpage 142 en_US SCI.Faculty of Science en_US
dc.conference Verified OK en_US
dc.for 070708 en_US
dc.personcode 0000061084 en_US
dc.personcode 0000061081 en_US
dc.personcode 0000022414 en_US
dc.personcode 105509 en_US
dc.personcode 910945 en_US
dc.personcode 0000052877 en_US
dc.percentage 70 en_US Veterinary Parasitology en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US en_US
dc.location.activity en_US
dc.description.keywords Neosporosis; Sheep; PCR; ELISA; Neospora caninum; Prevalence; Fatal neurological disease; Epidemiology en_US

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