Abstract:
As part of a programme of research to generate fully characterized aro- mutants of Salmonella typhi for use as live attenuated vaccines we have cloned and sequenced the aroC (1) and aroD genes (submitted to J. Gen. Microbiol.) of S. typhi. We report here the nucleotide sequence of the S. typhi aroA gene encoding 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase).