Pdz Domains Facilitate Binding Of High Temperature Requirement Protease A (Htra) And Tail-Specific Protease (Tsp) To Heterologous Substrates Through Recognition Of The Small Stable Rna A (Ssra)-Encoded Peptide

Abstract

The Escherichia coli protease HtrA has two PDZ domains, and sequence alignments predict that the E. coli protease Tsp has a single PDZ domain. PDZ domains are composed of short sequences (80-100 amino acids) that have been implicated in a range of protei