Synthesis of 2'-Aminoalkyl-1-benzylisoquinoline derivatives, medium sized ring analogues with mu opiod receptor binding activities

UTSePress Research/Manakin Repository

Search UTSePress Research


Advanced Search

Browse

My Account

Show simple item record

dc.contributor.author Mbere-Nguyen, U. en_US
dc.contributor.author Ung, Alison en_US
dc.contributor.author Pyne, Stephen en_US
dc.contributor.editor en_US
dc.date.accessioned 2011-02-07T06:18:47Z
dc.date.available 2011-02-07T06:18:47Z
dc.date.issued 2010 en_US
dc.identifier 2009004531 en_US
dc.identifier.citation Mbere-Nguyen U., Ung Alison, and Pyne Stephen 2010, 'Synthesis of 2'-Aminoalkyl-1-benzylisoquinoline derivatives, medium sized ring analogues with mu opiod receptor binding activities', Pergamon, vol. 66, no. 23, pp. 4133-4143. en_US
dc.identifier.issn 0040-4020 en_US
dc.identifier.other C1 en_US
dc.identifier.uri http://hdl.handle.net/10453/13097
dc.description.abstract Novel 20-aminoalkyl-1-benzylisoquinoline compounds and medium size ring analogues have been prepared using reductive alkylation methods. Four of these analogues were tested for biological activity across 48 different CNS receptors and were showed to have binding activities at the mu opiod receptor. en_US
dc.language en_US
dc.publisher Pergamon en_US
dc.relation.hasversion Accepted manuscript version en_US
dc.relation.isbasedon http://dx.doi.org/10.1016/j.tet.2010.03.110 en_US
dc.rights NOTICE: this is the author’s version of a work that was accepted for publication in Tetrahedron. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Tetrahedron, [VOL# 66 (2010) 4133–4143] doi:10.1016/j.tet.2010.03.110 en_US
dc.title Synthesis of 2'-Aminoalkyl-1-benzylisoquinoline derivatives, medium sized ring analogues with mu opiod receptor binding activities en_US
dc.parent Tetrahedron en_US
dc.journal.volume 66 en_US
dc.journal.number 23 en_US
dc.publocation United Kingdom en_US
dc.identifier.startpage 4133 en_US
dc.identifier.endpage 4143 en_US
dc.cauo.name SCI.Chemistry and Forensic Sciences en_US
dc.conference Verified OK en_US
dc.for 030500 en_US
dc.personcode 0000061576 en_US
dc.personcode 106546 en_US
dc.personcode 0000061573 en_US
dc.percentage 100 en_US
dc.classification.name Organic Chemistry en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords benzylisoquinolines alkaloids, CNS binding activities, mu opiod receptor en_US
dc.staffid en_US


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record