The roles of protein glycation, glycoxidation and advanced glycation end-product formation in diabetes-induced atherosclerosis

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dc.contributor.author Rashid, Imran en_US
dc.contributor.author Brown, Bronwyn en_US
dc.contributor.author Van Reyk, David en_US
dc.contributor.author Davies, Michael en_US
dc.contributor.editor Kaur, Sukhinder. C. en_US
dc.date.accessioned 2010-06-16T04:55:47Z
dc.date.available 2010-06-16T04:55:47Z
dc.date.issued 2006 en_US
dc.identifier 2006004361 en_US
dc.identifier.citation Rashid Imran et al. 2006, 'The roles of protein glycation, glycoxidation and advanced glycation end-product formation in diabetes-induced atherosclerosis', Springer, New York, USA, pp. 247-283. en_US
dc.identifier.issn 0387312528 en_US
dc.identifier.other B1 en_US
dc.identifier.uri http://hdl.handle.net/10453/11659
dc.description.abstract Diabetes is known to induce a range of micro-and macrovascular compliacations with the latter resutling in premature and accelerated atherosclerosis. Thus people with diabetes have a 2-4 fold increased risk of developing cardiovascular diseases which is responsible for ca. 50% of deaths amongst people with diabetes. The mechanisms behind this elevated risk are still not fully understood, though there is now increasing evidence for a role of glycation and clycoxidation reactions induced by hyperglycemia. This article reviews current knowledge of the role that these reactions play in diabetes-induced atherosclerosis with particular emphasis on the molecular reactions that result in the modification of lipoproteins, and the consequences of these reactions on cellular metabolism. en_US
dc.language en_US
dc.publisher Springer en_US
dc.relation.isbasedon en_US
dc.title The roles of protein glycation, glycoxidation and advanced glycation end-product formation in diabetes-induced atherosclerosis en_US
dc.parent Biochemistry of Atherosclerosis en_US
dc.journal.volume en_US
dc.journal.number en_US
dc.publocation New York, USA en_US
dc.identifier.startpage 247 en_US
dc.identifier.endpage 283 en_US
dc.cauo.name FEIT. A/DRsch Ctre for Health Technologies en_US
dc.conference Verified OK en_US
dc.for 110201 en_US
dc.personcode 0000028295 en_US
dc.personcode 0000028296 en_US
dc.personcode 000788 en_US
dc.personcode 0000045917 en_US
dc.percentage 100 en_US
dc.classification.name Cardiology (incl. Cardiovascular Diseases) en_US
dc.classification.type FOR-08 en_US
dc.edition 1 en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords en_US


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