http://hdl.handle.net/10453/284 2013-06-18T05:31:34Z http://hdl.handle.net/10453/14390 Optimisation Of The Separation Of Amino Acids By Capillary Electrophoresis Using Artificial Neural Networks Van Gramberg Amanda; Beavis Alison; Blanes Lucas; Doble Philip Grady Hanrahan and Frank A. Gomez Many factors can affect the separation performance of a capillary electrophoresis (CE) electrolyte, such as the buffer, surfactant and organic modifier concentrations, pH, capillary temperature, and applied voltage (1). The efficient manipulation of these factors is critical to optimize the resolution of a given analysis in the shortest time frame. During the method development process, an analyst will usually attempt a separation based on a previously reported method that is similar or the same as the requirements of the analysis at hand. If the separation is inadequate, a univariate approach (2) is often employed to attempt to improve the separation. This involves altering one parameter at a time in a systematic way, and viewing the results by plotting the effect of the parameter on the migration time of the analytes. In this way, suitable electrolyte compositions may be found that separates all of the analytes. If suitable conditions are not found, a second electrolyte parameter is chosen and altered in a similar manner. This univariate procedure is then repeated until a suitable condition is found. This method of optimization is time-consuming, and it is unknown if the optimum is truly the global optimum. 2010-01-01T00:00:00Z http://hdl.handle.net/10453/14389 Chemometric Methods Applied to Genetic Analyses by Capillary Electrophoresis and Electrophoresis Microchip Technologies Funes-Huacca Maribel; Alberice Juliana; Blanes Lucas; Carrilho Emanuel Grady Hanrahan and In this chapter we have summarized the complex issues that are involved in the analysis of sizing DNA by capillary electrophoresis (CE), and how chemometric methods can help to optimize a high number of interrelated variables. It is impressive to observe how diverse is the biological information obtainable despite the size of the double-stranded DNA molecule. We also briefly introduce some typical genetic assays that rely on sizing DNA molecules, and how some chemometric approaches are used to correlate sizes of DNA with population and or evolution of species. 2010-01-01T00:00:00Z http://hdl.handle.net/10453/14388 A sociocultural approach to motivation: A long time coming but here at last Walker Richard; Pressick-Kilborn Kimberley; Sainsbury Erica; Maccallum Judith Timothy C. Urdan & Stuart A. Karabenick Until recently, motivation has been considered to be an individual phenomenon. Motivational theorists have accordingly conceptualised key constructs in individualistic terms and emphasised the individual origins and nature of motivation, although they have also long recognised that contextual or social factors have a significant influence on these individual processes. Recently this conceptualisation has been questioned as theorists have suggested, after Vygotsky, that motivation, like learning and thinking, Illight be social in nature. This idea was first suggested by Sivan (1986) more than twenty years ago but it received a major impetus with the pnblication of an article by Hickey (1997) eleven years later. Since that time interest in the social nature of motivation has grown as a small number of book chapters and journal articles have been published and conference papers have been presented on the topic. 2010-01-01T00:00:00Z http://hdl.handle.net/10453/14387 Querying Queer Theory: Debating Male-Male Prostitution in the Chinese Media Jeffreys Elaine Rachel Murphy and Vanessa L Fong NA 2008-01-01T00:00:00Z