http://hdl.handle.net/10453/11587 2013-05-21T11:55:34Z http://hdl.handle.net/10453/19430 Strategies for Vaccination and Control of Apicomplexan Protozoan Parasites Wallach Michael A. Mendez-Vilas Over the past several decades a great deal of effort has been invested in developing new control and vaccination strategies for apicomplexan protozoan parasites. These organisms are the cause of some of the most significant and harmful diseases in both humans and animals worldwide and include as examples; Plasmodium (malaria) and Cryptosporidium in humans, Toxoplasma in humans and animals, Babesia and Neospora in cattle, and Eimeria the cause of coccidiosis in animals (poultry, sheep, cattle, etc.). In spite of a great deal of progress made in understanding at the molecular level how these organisms invade, survive and transmit in their respective hosts, there has been a paucity of new vaccines commercially developed against these parasitic protozoa over the past few decades. In this chapter, we will discuss the types of strategies being developed to help control these parasites, which includes the development of live and subunit (both native and recombinant DNA based) vaccines, the search for and use of new or existing drugs (such as artemisinin combination therapy against malaria), as well as simpler management & hygiene strategies that can be employed to help alleviate the burden of parasitic diseases. 2011-01-01T00:00:00Z http://hdl.handle.net/10453/17582 Structural Genomics of the Bacterial Mobile Metagenome: an Overview Robinson Andrew; Guilfoyle Amy; Sureshan Visaahini; Howell Michael; Harrop Stephen; Boucher Yan; Stokes Harold; Curmi Paul; Mabbutt Bridget B. Kobe, M. Guss and T. Huber 2008-01-01T00:00:00Z http://hdl.handle.net/10453/16739 Difficult proteins Herbert Ben; Harry Elizabeth David Sheehan and Raymond Tyther NA 2009-01-01T00:00:00Z http://hdl.handle.net/10453/16738 Bacterial partnerships enhance the value of native legumes in rehabilitation of degraded agricultural lands Thrall Peter; Murray Brad; Watkin Elizabeth; Woods Matthew; Baker Katherine; Burdon Jeremy; Brockwell John A consequence of the generally low nutrient levels of Australian soils is that relationships between plants and their microbial symbionts (mycorrhizal fungi as weJl as nitrogen-fixing bacteria) have particular significanc:e for conservation management, sustainable agriculture, and eco~ystem rehabilitation. Shrubby legumes in the Fabaceae (e.g. Acacia, Oaviesia, Oil/wynia, Oxylobium, Hovea and Pultenaea) constitute a major group of plants that form nitrogen- fixing (N2-fixin@) partnerships with root-nodule bacteria (species of rhizobia). These taxa are found throughout Australia, and are frequently a dominant part of undisturbed ecosystems, both in terms of abundance as well as overall biomass. 2001-01-01T00:00:00Z