Browsing by Author "Turcato S"

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Browsing by Author "Turcato S"

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  • Cardiac Transgenesis With The Tetracycline Transactivator Changes Myocardial Function And Gene Expression 
    Mccloskey Dt; Turnbull Lynne; Swigart Pm; Zambon Ac; Turcato S; Joho S; Grossman W; Conklin Br; Simpson Pc; Baker Anthony (Amer Physiological Soc, 2005)
    The cardiac-specific tetracycline-regulated gene expression system (tet-system) is a powerful tool using double-transgenic mice. The cardiac alpha-myosin heavy chain promoter (alpha MHC) drives lifetime expression of a ...
  • Expression Of A Gi-Coupled Receptor In The Heart Causes Impaired Ca2+ Handling, Myofilament Injury, And Dilated Cardiomyopathy 
    Mccloskey Dt; Turcato S; Wang Guan-Ying; Turnbull Lynne; Zhu Bo-Qing; Bambino T; Nguyen Ap; Lovett Dh; Nissenson Ra; Karliner Js; Baker Anthony (Amer Physiological Soc, 2008)
    Increased signaling by G(i)-coupled receptors has been implicated in dilated cardiomyopathy. To investigate the mechanisms, we used transgenic mice that develop dilated cardiomyopathy after conditional expression of a ...
  • Ischemic Preconditioning Depends On Age And Gender 
    Turcato S; Turnbull Lynne; Wang Guan-Ying; Honbo N; Simpson Pc; Karliner Js; Baker Anthony (Dr Dietrich Steinkopff Verlag, 2006)
    The goal of this study was to determine if an ischemic preconditioning (IPC) protocol improved post-ischemic functional recovery of female mouse hearts. A previous study found that IPC did not occur in hearts from 10-week-old ...
  • Sustained Preconditioning Induced By Cardiac Transgenesis With The Tetracycline Transactivator 
    Turnbull Lynne; Zhou Hong; Swigart Pm; Turcato S; Karliner Js; Conklin Br; Simpson Pc; Baker Anthony (Amer Physiological Soc, 2006)
    Preconditioning protocols that protect the heart from ischemic injury may aid in the development of new therapies. However, the temporal window of cardioprotection is limited to a few days after the preconditioning stimulus. ...