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Early hypothalamic FTO overexpression in response to maternal obesity - potential contribution to postweaning hyperphagia

Caruso V; Chen Hui; Morris Michael (Public Library Science, 2011)

Background: Intrauterine and postnatal overnutrition program hyperphagia, adiposity and glucose intolerance in offspring. Single-nucleotide polymorphisms (SNPs) of the fat mass and obesity associated (FTO) gene have been ...
Maternal cigarette smoke exposure contributes to glucose intolerance and decreased brain insulin action in mice offspring independent of maternal diet

Chen Hui; Iglesias Miguel; Caruso V; Morris Michael (Public Library Science, 2011)

Background: Maternal smoking leads to intrauterine undernutrition and is associated with low birthweight and higher risk of offspring obesity. Intrauterine smoke exposure (SE) may alter neuroendocrine mediators regulating ...

Now showing items 1-2 of 2