Browsing by Author "Lyle S"

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Browsing by Author "Lyle S"

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  • Loss of miRNA biogenesis induces p19(Arf)-p53 signaling and senescence in primary cells 
    Mudhasani R; Zhu Zq; Hutvagner Gyorgy; Eischen Cm; Lyle S; Hall Ll; Lawrence Jb; Imbalzano An; Jones Sn (Rockefeller Univ Press, 2008)
    Dicer, an enzyme involved in microRNA (miRNA) maturation, is required for proper cell differentiation and embryogenesis in mammals. Recent evidence indicates that Dicer and miRNA may also regulate tumorigenesis. To better ...