Browsing by Author "Lockett, Lj"

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Browsing by Author "Lockett, Lj"

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  • Garcia-Aragon, J; Daja, Mm; Russell, P; Both, Gw; Molloy, Pl; Lockett, Lj; Russell, Pj; Martiniello-Wilks, Rose (Mary Ann Liebert Inc Publ, 1998)
    Advanced prostate cancer is invariably lethal once it becomes androgen independent (AI). With the aim of developing a new treatment we have used the human androgen-independent prostate cancer cell line, PC-3, to evaluate ...
  • Russell, Pj; Lockett, Lj; Brookes, Diana; Zandvliet, D; Watt, F; Molloy, Pl; Khatri, A; Both, Gw; Martiniello-Wilks, Rose (Australian Biotechnology Assoc Ltd, 1998)
    Recent developments in molecular biology have provided the opportunity for new gene therapy-based approaches for treating prostate cancer. A range of approaches are being taken for different cancer types, with over a hundred ...
  • Tsatralis, Tania; Russell, P; Brookes, Diana; Zandvliet, D; Lockett, Lj; Both, Gw; Molloy, Pl; Russell, Pj; Martiniello-Wilks, Rose (Nature Publishing Group, 2002)
    The Escherichia coli enzyme (purine nucleoside phosphorylase, PNP) gene is delivered directly into PC3 tumors by one injection of replication-deficient human type-5 adenovirus (Ad5). Expressed PNP converts the systemically ...