Browsing by Author "Lai Angela"

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Browsing by Author "Lai Angela"

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  • Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer 
    Arndt Greg; Dossey Lesley; Cullen Lara; Lai Angela; Druker Riki; Eisbacher Michael; Zhang Chunyan; Tran Nham; Fan Hongtao; Retzlaff Kathy; Bittner Anton; Raponi Mitch (BioMed Central Ltd., 2009)
    Background MicroRNAs (MiRNAs) are short non-coding RNAs that control protein expression through various mechanisms. Their altered expression has been shown to be associated with various cancers. The aim of this study was ...
  • RNA modulators of complex phenotypes in mammalian cells 
    Lai Angela; Cairns Murray; Tran Nham; Zhang Hong-Ping; Cullen Lara; Arndt Greg (Public library of Science, 2009)
    RNA-mediated gene silencing, in the form of RNA interference (RNAi) or microRNAs (miRNAs) has provided novel tools for gene discovery and validation in mammalian cells. Here, we report on the construction and application ...