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Combination of cytosine deaminase with uracil phosphoribosyl transferase leads to local and distant bystander effects against RM1 prostate cancer in mice

Khatri A; Zhang Bingsen; Doherty E; Chapman John; Ow K; Pwint H; Martiniello-Wilks Rosetta; Russell Pj (John Wiley & Sons Ltd, 2006)

Background We aimed to evaluate the efficacy of gene-directed enzyme-prodrug therapy (GDEPT) using cytosine deaminase in combination with uracil phosphoribosyl transferase (CDUPRT) against intraprostatic mouse androgen-refractory ...
Concise Review: Nanoparticles And Cellular Carriers-Allies In Cancer Imaging And Cellular Gene Therapy?

Tang Chiu; Russell Pj; Martiniello-Wilks Rosetta; Rasko J; Khatri A (Alphamed Press, 2010)

Ineffective treatment and poor patient management continue to plague the arena of clinical oncology. The crucial issues include inadequate treatment efficacy due to ineffective targeting of cancer deposits, systemic ...
Prostate cancer gene therapy

Russell Pj; Martiniello-Wilks Rosetta; Lockett Lj; Brookes Diana; Zandvliet D; Watt F; Molloy Pl; Khatri A; Both Gw (Australian Biotechnology Assoc Ltd, 1998)

Recent developments in molecular biology have provided the opportunity for new gene therapy-based approaches for treating prostate cancer. A range of approaches are being taken for different cancer types, with over a hundred ...

Now showing items 1-3 of 3