Browsing by Author "Jaiswal Ritu"

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Browsing by Author "Jaiswal Ritu"

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  • Membrane microparticles mediate transfer of P-glycoprotein to drug sensitive cancer cells 
    Bebawy Mary; Combes Valery; Lee E; Jaiswal Ritu; Gong J; Bonhoure A; Grau Georges (Nature Publishing Group, 2009)
    Multidrug resistance (MDR), a significant impediment to the successful treatment of cancer clinically, has been attributed to the overexpression of P-glycoprotein (P-gp), a plasma membrane multidrug efflux transporter. ...
  • Microparticle-associated nucleic acids mediate trait dominance in cancer 
    Jaiswal Ritu; Gong Joyce; Sambasivam Shwetha; Combes Valery; Mathys Jean-Marie; Davey Ross; Grau Georges; Bebawy Mary (Federation of American Societies for Experimental Biology, 2012)
    Drug resistance is a major cause of cancer treatment failure, with multidrug resistance (MDR) being the most serious, whereby cancer cells display cross-resistance to structurally and functionally unrelated drugs. MDR is ...
  • Time- and passage-dependent characteristics of a Calu-3 respiratory epithelial cell model 
    Haghi M; Young P M; Traini D; Jaiswal Ritu; Gong J; Bebawy Mary (Taylor & Francis Inc, 2010)
    Background: Although Standard Protocols For The Study Of Drug Delivery In The Upper Airways Using The Sub-Bronchial Epithelial Cell Line Calu-3 Model, Particularly That Of The Air-Liquid Interface Configuration, Are Readily ...