Browsing by Author "Holmes Ls"

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Browsing by Author "Holmes Ls"

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  • Cloning And Expression Of A Rat Neuronal Nitric-Oxide Synthase Coding Sequence In A Baculovirus-Insect Cell System 
    Charles Ian; Chubb A; Gill R; Clare J; Lowe Pn; Holmes Ls; Page M; Keeling Jg; Moncada S; Riverosmoreno V (Academic Press Inc Elsevier Science, 1993)
    A DNA sequence encoding rat neurorial NO synthase (nNOS) was isolated and cloned into the baculovirus expression vector pVL1393 to generate pVLRBNOS. Transfection of Spodoptera frugiperda Sf-21 cells with the construct ...
  • Roles Of Nitric-Oxide In Tumor-Growth 
    Jenkins David; Charles Ian; Thomsen Ll; Moss D; Holmes Ls; Baylis Sa; Rhodes P; Westmore K; Emson Pc; Moncada S (Natl Acad Sciences, 1995)
    A subclone of the human colon adenocarcinoma cell line DLD-1, which grew reproducibly as subcutaneous tumors in nude mice, was isolated. Such cells, when engineered to generate nitric oxide (NO) continuously, grew more ...