Browsing by Author "Holmes Andrew"

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Browsing by Author "Holmes Andrew"

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  • The Evolution of Class 1 Integrons and the Rise of Antibiotic Resistance 
    Gillings Michael; Boucher Yan; Labbate Maurizio; Holmes Andrew; Krishnan Samyuktha; Holley Marita; Stokes Harold (Amer Soc Microbiology, 2008)
    Class 1 integrons are central players in the worldwide problem of antibiotic resistance, because they can capture and express diverse resistance genes. In addition, they are often embedded in promiscuous plasmids and ...
  • Recombination Activity of a Distinctive Integron-Gene Cassette System Associated with Pseudomonas stutzeri Populations in Soil 
    Holmes Andrew; Holley Marita; Mahon Andrew; Nield Blair; Gillings Michael; Stokes Harold (Amer Soc Microbiology, 2003)
    Class 1 integrons have strongly influenced the evolution of multiple antibiotic resistance. Diverse integrons have recently been detected directly in a range of natural environments. In order to characterize the properties ...
  • Recovery of new integron classes from environmental DNA 
    Nield Blair; Holmes Andrew; Gillings Michael; Recchia Gavin; Mabbutt Bridget; Nevalainen Helena; Stokes Harold (Elsevier Inc, 2001)
    Integrons are genetic elements known for their role in the acquisition and expression of genes conferring antibiotic resistance. Such acquisition is mediated by an integron-encoded integrase, which captures genes that are ...
  • What are superintegrons? 
    Hall Ruth; Holmes Andrew; Roy Paul; Stokes Harold (Nature Publishing Group, 2007)