Browsing by Author "Coyne Jj"

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Browsing by Author "Coyne Jj"

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  • Evidence For Associations Between The Purinergic Receptor P2X(7) (P2Rx7) And Toxoplasmosis 
    Jamieson S; Peixoto-Rangel Al; Hargrave Ac; De Roubaix La; Mui Ej; Boulter Nicola; Miller En; Fuller Stephen; Wiley James; Castellucci L; Boyer K; Peixe Rg; Kirisits Mj; Elias Ld; Coyne Jj; Correa-Oliveira R; Sautter M; Smith Narelle; Lees Michael; Swisher Cn; Heydemann P; Noble A; Patel D; Bardo D; Burrowes D; Mclone D; Roizen N; Withers S; Bahia-Oliveira Lmg; Mcleod R; Blackwell J (Nature Publishing Group, 2010)
    Congenital Toxoplasma gondii infection can result in intracranial calcification, hydrocephalus and retinochoroiditis. Acquired infection is commonly associated with ocular disease. Pathology is characterized by strong ...
  • P2X7 receptor-mediated killing of an intracellular parasite, Toxoplasma gondii, by human and murine macrophages 
    Lees Michael; Fuller Stephen; Mcleod R; Boulter Nicola; Miller Catherine; Zakrzewski Alana; Mui Ej; Witola William; Coyne Jj; Hargrave Ac; Jamieson S; Blackwell J; Wiley James; Smith Nicholas (American Association of Immunologists, 2011)
    The P2X7R is highly expressed on the macrophage cell surface, and activation of infected cells by extracellular ATP has been shown to kill intracellular bacteria and parasites. Furthermore, single nucleotide polymorphisms ...