Wang Xiu-Hong; Martiniello-Wilks Rosetta; Shaw Jeffrey; Ho T; Coulston N; Cooke-Yarborough C; Molloy Pl; Cameron Fiona; Moghaddam Matthew; Lockett Tj; Webster Lk; Smith Ian; Both Gw; Russell Pj
(Nature Publishing Group, 2004)
Gene-directed enzyme prodrug therapy (GDEPT) based on the Escherichia coli enzyme, purine nucleoside phosphorylase (PNP), provides a novel strategy for treating slowly growing tumors like prostate cancer (CaP). PNP converts ...